Zerbaxa 1.5 g is an antibiotic use to treat adults and children with: Zerbaxa Ceftolozane sodium in india sulfate and tazobactam sodium price best at Yourmedikart online
- Complicate (difficult to treat) infections of tissues and organs within the belly (intra-abdominal infections)
- Serious kidney infection (acute pyelonephritis)
- Complicate infections of the urinary tract (structures that carry urine, such as the bladder).
It is also use to treat adults with hospital-acquire pneumonia (an infection of the lungs that is caught in the hospital), including ventilator-associate pneumonia.
Zerbaxa 1.5 g price in india contains the active substances ceftolozane and tazobactam.
Generic name: Ceftolozane sulfate and tazobactam sodium
Dosage form: injection, powder, lyophilized, for solution.
Drug class: Cephalosporins / beta-lactamase inhibitors
J Code (medical billing code): J0695 (Ceftolozane 50 mg-tazobactam 25 mg, intravenous)
What is Zerbaxa?
- Zerbaxa is a combination antibiotic that is use to treat certain bacterial infections of the lungs, stomach, or urinary tract.
- Zerbaxa 1.5 g price in india is sometimes given in combination with another antibiotic medicine.
- Zerbaxa may also be use for purposes do not list in this medication guide.
How is Zerbaxa used?
- Explore the effective treatment options with Zerbaxa, a prominent medication used for battling bacterial infections.
- Get insights into the Zerbaxa dosage and Zerbaxa dose recommendations, as well as the Zerbaxa price and Zerbaxa cost to assist with your medical budgeting.
- For those needing specific dosage adjustments, particularly in renal care, review the Piptaz renal dose and renal dose of Piptaz.
- Additionally, you can find details on Piptaz dose and Piptaz adult dose for broader application needs. Interested in pediatric care? Check the Piptaz paediatric dose and other related medications like Dicloxacillin ped dose and Dicloxacillin renal dose.
- Learn more about the active ingredients in Zerbaxa, such as Ceftolozane and Tazobactam, and their combinations like Ceftolozane/Tazobactam and the broader availability such as Ceftolozane Tazobactam India.
- Whether you’re looking for generic options or brand names, this comprehensive resource will aid in understanding the full spectrum of treatment possibilities.
- Zerbaxa is available for infusion (drip) into a vein and can only be obtain with a prescription. It is given over 1 hour, every 8 hours. The dose and duration of treatment depend on the infection treat and how the infection responds to the medicine. For children the dose and duration also depend on body weight.
- For more information about using Zerbaxa, see the package leaflet or contact your doctor or pharmacist.
Zerbaxa given
- Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as direct. This medicine is sometimes given for up to 14 days, depending on the type of infection being treated.
- Zerbaxa 1.5 g price in india is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.
- Read and carefully follow any Instructions for Use provide with your medicine. Ask your doctor or pharmacist if you don’t understand all instructions.
- Prepare an injection only when you are ready to give it. Do not use if the medicine has change colors or has particles in it. Call your pharmacist for new medicine.
- Zerbaxa must be mix with a liquid (diluent) and then further dilute with another liquid in an IV bag. When using injections by yourself, be sure you understand how to properly mix and store the medicine.
- Use this medicine for the full prescribe length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Zerbaxa will not treat a viral infection such as the flu or a common cold.
- Store the unmix Zerbaxa powder in a refrigerator. Protect from light.
- After you mix the powder with the first diluent, store this mixture at room temperature for up to 1 hour before further mixing it into the IV bag.
- Medicine mix in an IV bag must be use within 24 hours if you keep it at room temperature, or within 7 days if kept in a refrigerator. Throw away any unuse mixture that has not been use within these times.
How Zerbaxa work?
- The active substances in Zerbaxa 1.5 g, ceftolozane and tazobactam, work in different ways. Ceftolozane is a type of antibiotic call a cephalosporin, which belongs to the wider group of antibiotics call beta-lactams.
- It works by interfering with the production of molecules that bacteria need to build their protective cell walls. This causes weakness in the bacterial cell walls which then become prone to collapse, ultimately leading to the death of the bacteria.
- Tazobactam blocks the action of bacterial enzymes call beta-lactamases. These enzymes enable bacteria to break down beta-lactam antibiotics like ceftolozane, making the bacteria resistant to the antibiotic’s action.
- By blocking the action of these enzymes, tazobactam allows ceftolozane to act against bacteria that would otherwise be resistant to this antibiotic.
- Zerbaxa tazobactam 1.5 g sodium metronidazole is indicate for the treatment.
Before taking this medicine
- You should not use Zerbaxa 1.5 g price in india if you are allergic to ceftolozane or tazobactam, or if you are allergic to similar antibiotics, such as:
- Penicillin antibiotics–amoxicillin, ampicillin, dicloxacillin, oxacillin, penicillin, ticarcillin, Amoxil, Moxatag, Augmentin, Principen, and others; or
- Cephalosporin antibiotics–Cefdinir, Cefprozil, Cefuroxime, Cephalexin, Ceftin, Cefzil, Keflex, Omnicef, and others.
- Kidney disease (or if you are on dialysis).
- Tell your doctor if you are pregnant or breastfeeding.
- Zerbaxa, with its effective formulation, is utilized for treating complex infections. The Zerbaxa price and availability of Zerbaxa generic options make it accessible for varied healthcare needs. Pediatric and renal dosing specifics, such as inj piptaz dose in pediatrics and dicloxacillin renal dose, are crucial for safe administration.
- The Zerbaxa 1.5g pack offers a comprehensive treatment dose, with potential Zerbaxa side effects detailed for informed use. Further information on its active component, ceftolozane, enhances understanding of its antibacterial properties.
Indications and Usage for Zerbaxa
- Zerbaxa (Ceftolozane and tazobactam) is a combination of Ceftolozane, a cephalosporin antibacterial, and tazobactam, a beta-lactamase inhibitor, indicate for the treatment of the following infections cause by designate susceptible microorganisms:
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- Complicate Intra-abdominal Infections (cIAI), use in combination with metronidazole, in adult and pediatric patients (birth to less than 18 years old).
- Complicate Urinary Tract Infections (cUTI), Including Pyelonephritis, in adult and pediatric patients (birth to less than 18 years old).
- Hospital-acquire Bacterial Pneumonia and Ventilator-associate Bacterial Pneumonia (HABP/VABP), in adult patients 18 years and older.
To reduce the development of drug-resistant bacteria and maintain the effectiveness of ZERBAXA 1.5 g tazobactam price and other antibacterial drugs, ZERBAXA should be use only to treat or prevent infections that are proven or strongly suspect to be cause by bacteria.
What benefits of Zerbaxa have been shown in studies?
- Zerbaxa has been shown to be at least as effective as other antibiotics in curing infections in three main studies.
- One study involve 1,083 adults who mostly had kidney infection or in some cases a complicate urinary-tract infection. Zerbaxa successfully treat the infection in about 85% of the cases where it was given (288 of 340), compare with 75% (266 of 353) of those given another antibiotic call levofloxacin.
- The second study involve 993 adults with complicate intra-abdominal infections. Zerbaxa was compare with another antibiotic, meropenem. Both medicines cure 94% of patients (353 out of 375 given Zerbaxa and 375 out of 399 given meropenem).
- The third study involve 726 adults who were using a ventilator and who had either hospital-acquire pneumonia or ventilator-associate pneumonia. It found Zerbaxa to be at least as effective as meropenem: the infection had resolve in 54% of patients (197 out of 362) after 7 to 14 days of treatment with Zerbaxa compare with 53% of patients (194 out of 362) on meropenem.
- Three studies conduct in children younger than 18 years old show that the way Zerbaxa is absorb, modify and remove from the body in this age group and in adults is similar. Zerbaxa is therefore expect to show similar effectiveness.
Warnings and Precautions
- Decrease efficacy was observe in a Phase 3 cIAI trial in a subgroup of patients with baseline CrCl of 30 to 50 mL/min. Monitor CrCl at least daily in patients with changing renal function and adjust the dose of Zerbaxa accordingly.
- Serious hypersensitivity (anaphylactic) reactions have report with beta-lactam antibacterial drugs. Exercise caution in patients with known hypersensitivity to beta-lactam antibacterial drugs. If an anaphylactic reaction to Zerbaxa occurs, discontinue the drug and institute appropriate therapy.
- Clostridioides difficile-associate diarrhea (CDAD) has report with nearly all systemic antibacterial agents, Zerbaxa 1.5 g Ceftolozane sulfate including ZERBAXA. Evaluate if diarrhea occurs.
Full Prescribing Information
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Indications and Usage for Zerbaxa
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- Complicate Intra-abdominal Infections
- ZERBAXA use in combination with metronidazole is indicate for the treatment of adult and pediatric patients (birth to less than 18 years old) with complicate intra-abdominal infections (cIAI) cause by the following susceptible Gram-negative and Gram-positive microorganisms:
- Enterobacter cloacae, Escherichia coli, Klebsiella Oxytoca, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Bacteroides fragilis, Streptococcus Anginosus, Streptococcus Constellatus, and Streptococcus salivarius.
- Zerbaxa, with its effective formulation, is utilized for treating complex infections. The Zerbaxa price and availability of Zerbaxa generic options make it accessible for varied healthcare needs. Pediatric and renal dosing specifics, such as inj piptaz dose in pediatrics and dicloxacillin renal dose, are crucial for safe administration.
- The Zerbaxa 1.5g pack offers a comprehensive treatment dose, with potential Zerbaxa tazobactam sodium in india side effects detailed for informed use. Further information on its active component, ceftolozane, enhances understanding of its antibacterial properties.
-
Complicate Urinary Tract Infections, Including Pyelonephritis
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- Zerbaxa Ceftolozane sulfate is indicate for the treatment of adult and pediatric patients (birth to less than 18 years old) with complicate urinary tract infections (cUTI)
- including pyelonephritis, cause by the following susceptible Gram-negative microorganisms: Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa.
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Hospital-acquire Bacterial Pneumonia and Ventilator-associate Bacterial Pneumonia (HABP/VABP)
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- Zerbaxa Ceftolozane sulfate is indicate for the treatment of adult patients (18 years and older) with hospital-acquire bacterial pneumonia and ventilator-associate bacterial pneumonia (HABP/VABP)
- Cause by the following susceptible Gram-negative microorganisms: Enterobacter cloacae, Escherichia coli, Haemophilus influenzae, Klebsiella Oxytoca, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, and Serratia marcescens.
Usage
- To reduce the development of drug-resistant bacteria and maintain the effectiveness of Zerbaxa tazobactam sodium in india Ceftolozane sulfate and other antibacterial drugs, Zerbaxa should be use only to treat or prevent infections that are proven or strongly suspect to be cause by susceptible bacteria.
- When culture and susceptibility information are available, they should consider in selecting or modifying antibacterial therapy. In the absence of such data, Zerbaxa 1.5 g Ceftolozane sulfate local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Zerbaxa Dose
- Zerbaxa is a crucial antibiotic, and if you are considering its use, it’s essential to know the Zerbaxa cost and Zerbaxa tazobactam sodium in india price, especially if you need Zerbaxa generic options.
- It’s important to check the Zerbaxa prezzo and Zerbaxa pret if you’re comparing global pricing. The Zerbaxa dose and Zerbaxa costo may vary based on treatment duration, so it is crucial to consider the Zerbaxa cost per day and prescribed Zerbaxa dosage.
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- For hospitals, the Zerbaxa iv cost is an essential factor. Zerbaxa comes in doses like Zerbaxa 1 5g and is available in forms like Zerbaxa tablet and Zerbaxa 1.5g. Be aware of Zerbaxa side effects
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Zerbaxa Dosage and Administration
Recommend Dosage in Adult Patients
- The recommend dosage of Zerbaxa 1.5 g tazobactam sodium in india price sodium in adult patients 18 years. And older with creatinine clearance (CrCl) greater than 50 mL/min is 1.5-gram ceftolozane 1 g and tazobactam 0.5 g for cIAI and cUTI and 3 g for HABP/VABP administer every 8 hours by intravenous infusion over 1 hour.
- The duration of therapy should guide by the severity and site of infection and the patient’s clinical and bacteriological progress as show in Table 1.
| Infection | Dose | Frequency | Infusion Time | Duration of Treatment |
|---|---|---|---|---|
| Complicate Intra-abdominal Infections† | 1.5 g | Every 8 Hours | 1 hour | 4 to 14 days |
| Complicate Urinary Tract Infections, Including Pyelonephritis | 1.5 g | Every 8 Hours | 1 hour | 7 days. |
| Hospital-acquire Bacterial Pneumonia and Ventilator-associate Bacterial Pneumonia (HABP/VABP) | 3 g | Every 8 Hours | 1 hour | 8 to 14 days. |
What are the risks associate with Zerbaxa?
- The most common side effects with Zerbaxa 1.5 g Ceftolozane sulfate sodium are nausea. Headache, constipation, diarrhea, fever and increase liver enzyme levels. Side effects in children are similar to those in adults, with the following additional common side effects:
- low levels of neutrophils (a type of white blood cell), increase appetite, and dysgeusia (taste disturbance).
- There is little data on the side effects of Zerbaxa tazobactam 1.5 g sodium in india for children younger than 3 months of age with complicate intra-abdominal infections. For the full list of side effects of Zerbaxa Ceftolozane sulfate, see the package leaflet.
- Zerbaxa tazobactam 1.5 g sodium in india must not use in people who are hypersensitive (allergic). To Zerbaxa Ceftolozane sulfate or any of its ingredients. Or in those who are hypersensitive to other cephalosporin antibiotics. Or have ever had a severe allergic reaction to another beta-lactam antibiotic.
Why is Zerbaxa tazobactam sodium Authorise in the EU?
- The European Medicines Agency decide that Zerbaxa 1.5 g Ceftolozane sulfate benefits. Are greater than its risks and it can be Authorise for use in the EU.
- The Agency consider that Zerbaxa Ceftolozane sulfate was effective at curing infections. In the patients study but acknowledge that only a limit number of patients with complicate urinary tract infections had include.
- The Agency also note that Tazobactam is not active against some classes of beta-Lactamase that can cause problems of resistance. Regarding safety, side effects were consider to be typical and expect for an Antibiotic of this kind.
Zerbaxa side effects
Get emergency medical help if you have signs of an Allergic reaction: hives. Zerbaxa tazobactam price sodium difficult Breathing; Swelling of your face, lips, tongue, or throat.
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Zerbaxa Ceftolozane sulfate may cause serious side effects. Call your doctor at once if you have:
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- Severe stomach pain
- Diarrhea that is watery or bloody (even if it occurs months after your last dose)
- Kidney Problems–little or no Urination, Swelling in your feet or ankles, feeling tired or short of breath; or
- Symptoms of Bleeding in the Brain–Sudden Numbness or Weakness, problems with vision or speech.
Side effects may more likely in older adults.
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Common side effects of Zerbaxa Ceftolozane sulfate may include:
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- Nausea, Diarrhea
- Headache
- Fever
- Kidney problems; or
- Abnormal liver function tests.
Warnings
- Follow all directions on your medicine label and package. Zerbaxa 1.5 g Tazobactam price Zerbaxa 1.5 g Ceftolozane sulfate Tazobactam sodium. Tell each of your Healthcare Providers about all your Medical Conditions, Allergies, and all medicines you use.
- Zerbaxa, a Combination of Ceftolozane and Tazobactam 1.5, is a powerful Antibiotic use in the treatment of Bacterial Infections. Its dosing and Reconstitution guidelines are crucial for ensuring Effectiveness and Minimizing side effects.
- Healthcare Providers can Reference its J code for billing and Prescribing information for detailed usage Instructions. Although Zerbaxa 1.5 g Ceftolozane sulfate is available as a generic, understanding its unique components. Ceftolozane/Tazobactam, and their roles, is essential for tailor patient care.
- Zerbaxa dosing, Including Dicloxacillin Pediatric dose and inj piptaz Pediatric dose, should closely follow to address various patient needs.
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