Retevmo Selpercatinib 40mg tab price in India get best at Yourmedikart.

• Generic Name: Selpercatinib capsules
• Brand Name: Retevmo
• Drug Class: Antineoplastics, VEGF Inhibitor, RET Kinase Inhibitors

What is Retevmo?

• Retevmo 40mg is a prescription medicine that is used to treat certain cancers caused by abnormal RET genes.
• Secondly, Retevmo is used in adults with locally advanced non-small cell lung cancer or NSCLC that has spread.
• Retevmo 40mg is used in adults and children 12 years of age and thyroid capsule name older with advanced medullary thyroid cancer or MTC that has spread, who require a medicine by mouth or injection.
• Retevmo is used in adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer. However, that has spread who require medicine by mouth or injection, and who have received radioactive iodine, and it did not work or is no longer working.
• Retevmo is also used in adults with locally advanced solid tumors or solid tumors that have spread and have gotten worse on or after other treatments or there are no satisfactory treatment options.

Your healthcare provider will perform a test to make sure that Retevmo is right for you.

It is not known if Retevmo is safe and effective when used:

• In children younger than 12 years of age for the treatment of MTC who require systemic therapy, retevmo dosing and advanced thyroid cancer who require systemic therapy and who have received radioactive iodine, and it did not work or is no longer working, or
• In children for the treatment of any other cancers.

Retevmo and how is it used?

Retevmo is a prescription medicine that is used to treat certain cancers caused by abnormal RET genes in:

• Adults with non-small cell lung cancer (NSCLC) that has spread.
• Adults and children 12 years of age and older with advanced medullary thyroid cancer or MTC that has spread retevmo selpercatinib 40mg tab price in india minimal at Yourmedikart. who require medicine by mouth or injection (systemic therapy).
• Thirdly Adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer Retevmo selpercatinib 40mg tab price in India minimal at Yourmedikart. that has spread who require medicine by mouth or injection (systemic therapy) and who have received radioactive iodine and it not work or is no longer working.
• Your healthcare provider will perform a test to make sure that Retevmo is right for you. It is not known if Retevmo is safe and effective in children younger than 12 years of age.

Before taking Retevmo

Before you start treatment, tell your healthcare provider about all your medical conditions, including if you:

• Have liver problems.
• Have high blood pressure.
• Similarly Have heart problems including a condition called QT prolongation.
• Have bleeding problems.
• Plan to have surgery. You should stop taking Retevmo at least 7 days before your planned surgery. selpercatinib 40mg price in india minimal at Yourmedikart. See Retevmo side effects.
• Are pregnant or plan to become pregnant. Retevmo can harm your unborn baby. You should not become pregnant during treatment.

• • If you are able to become pregnant, your healthcare provider will do a pregnancy test before you start treatment.
  • Females who are able to become pregnant should use effective birth control (contraception) during treatment and for at least 1 week after the final dose. Retevmo selpercatinib 40mg tab price in India Best at Yourmedikart. Talk to your healthcare provider about birth control methods that may be right for you.
  • Tell your healthcare provider right away if you become pregnant or think you might be pregnant during treatment.
  • Males with female partners who are able to become pregnant should use effective birth control during treatment and for at least 1 week after the final dose.
  • Are breastfeeding or plan to breastfeed? It is not known if Retevmo passes into your breast milk. Do not breastfeed during treatment, and for 1 week after the last dose.

What other drugs will affect Retevmo Selpercatinib?

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I Take Retevmo Selpercatinib?

• Take Retevmo selpercatinib 40mg tab exactly as your healthcare provider tells you.
• Your healthcare provider may stop treatment or change your dose if you have side effects. Do not change your dose or stop treatment unless your healthcare provider tells you.
• Retevmo selpercatinib 40mg tab price is taken by mouth, usually 2 times a day with or without food.
• If you take a proton-pump inhibitor, take Retevmo with food.
• If you take an antacid that contains aluminum, magnesium, calcium, simethicone, or buffered medicines, take Retevmo 2 hours before or 2 hours after taking the antacid.
• If you take an H2 blocker, take Retevmo 2 hours before or 10 hours after taking the H2 blocker.
• Swallow Retevmo capsules whole. Do not chew or crush the capsules.
• If you vomit after taking a dose, do not take an extra dose. Take the next dose at your scheduled time.
• Do not take a missed dose unless it is more than 6 hours until your next scheduled dose.
• If you take too much Retevmo, call your healthcare provider or go to the nearest hospital emergency room right away.

Dosing information

Usual Adult Dose for Non-Small Cell Lung Cancer:

• • Less than 50 kg: 120 mg orally 2 times daily until disease progression or unacceptable toxicity.
  • 50 kg or greater: 160 mg orally 2 times daily until disease progression or unacceptable toxicity.
    Use: For the treatment of adult patients with metastatic RET fusion-positive non-small cell lung cancer (NSCLC)

Adult Dose for Thyroid Cancer:

• • Less than 50 kg: 120 mg orally 2 times daily until disease Retevmo selpercatinib 40 mg price in india progression or unacceptable toxicity
  • 50 kg or greater: 160 mg orally 2 times daily until disease progression or unacceptable toxicity uses:
    -For the treatment of adult patients with advanced or metastatic RET-mutant medullary thyroid cancer (MTC) who require systemic therapy.
    -For the treatment of adult patients with advanced or metastatic RET fusion-positive thyroid cancer selpercatinib price who require systemic therapy and who are radioactive iodine-refractory (if radioactive iodine is appropriate)

Usual Pediatric Dose for Thyroid Cancer:

• 12 years and older:
• Less than 50 kg: 120 mg orally 2 times daily until disease progression or unacceptable toxicity
• 12 years and older:
  50 kg or greater: 160 mg orally 2 times daily until disease progression or unacceptable toxicity

Uses:
-For the treatment of Pediatric patients 12 years and older with advanced or metastatic RET-mutant medullary thyroid cancer (MTC) who require systemic therapy
-For the treatment of Pediatric patients 12 years and older with advanced or metastatic RET fusion-positive thyroid cancer who require systemic therapy and who are radioactive iodine-refractory 

Usual Adult Dose for Solid Tumors:

• Less than 50 kg: 120 mg orally 2 times daily until disease progression or unacceptable toxicity
• 50 kg or greater: 160 mg orally 2 times daily until disease progression or unacceptable toxicity

• Use:
  -For the treatment of adult patients with advanced or metastatic RET-mutant solid tumors who have progressed on or following prior systemic treatment or who have no satisfactory alternative treatment options.
  This indication is approved under accelerated approval based on overall response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trial(s). 

Retevmo Selpercatinib Side Effects

Retevmo Selpercatinib may cause serious side effects, including:

• Liver problems. 

• • Liver problems (increased liver enzymes) are common with Retevmo and may sometimes be serious.
  • Your healthcare provider will do blood tests before and during treatment to check for liver problems.
  • Tell your healthcare provider right away if you get any of the following symptoms of liver problems during treatment:

• • • Yellowing of your skin or the white part of your eyes (jaundice)
    • Dark “tea-colored” urine
    • Sleepiness
    • Bleeding or bruising
    • Loss of appetite
    • Nausea or vomiting
    • Pain on the upper right side of your stomach area

• Lung problems.

• •  Retevmo may cause severe or life-threatening inflammation of the lungs during treatment, that can lead to death.
  • Secondly Tell your healthcare provider right away if you have any new or worsening lung symptoms, including:

• • • Shortness of breath
    • Cough
    • Fever

• High blood pressure (hypertension).

• • Firstly High blood pressure is common with Retevmo and may sometimes be serious.
  • So, You should check your blood pressure regularly during treatment.
  • Tell your healthcare provider if you get any of the following symptoms:

• • • Confusion
    • Headaches
    • Shortness of breath
    • Dizziness
    • Chest pain

• Heart rhythm changes (QT prolongation) 

  • Heart rhythm changes can occur and may be serious. Retevmo may cause very slow, very fast or irregular heartbeats.
  • Moreover, tell your healthcare provider right away if you get any of the following symptoms:
    • Loss of consciousness
    • Fainting
    • Dizziness
    • A change in the way your heart beats (heart palpitations)

• Bleeding problems. 

• • Retevmo can cause bleeding which can be serious and may lead to death.
  • In Addition Tell your healthcare provider if you have any signs of bleeding during treatment, including:

• • • Vomiting blood or if your vomit looks like coffee-grounds
    • Pink or brown urine
    • Red or black (looks like tar) stools
    • Coughing up blood or blood clots
    • Unusual bleeding or bruising of your skin
    • Menstrual bleeding that is heavier than normal
    • Unusual vaginal bleeding
    • Nose bleeds happen often
    • Drowsiness or difficulty being awakened
    • Confusion
    • Headache
    • Change in speech

• Allergic reactions.

• • Retevmo can cause a fever, rash, and muscle or joint pain, especially in the first month of treatment.
  • And Tell your healthcare provider if you get any of these symptoms.

• Tumor lysis syndrome (TLS).

  • TLS is caused by a fast breakdown of cancer cells. TLS can cause kidney failure, the need for dialysis treatment, and an abnormal heartbeat.
  • TLS can lead to hospitalization. Moreover, your healthcare provider may do blood tests to check you for TLS.
  • You should stay well hydrated during treatment with Retevmo. After that Call your healthcare provider or get emergency medical help right away if you develop any of these symptoms during treatment with Retevmo:
    • Nausea
    • Shortness of breath
    • Vomiting
    • Muscle cramps
    • Weakness
    • Seizures
    • Swelling

• Risk of wound healing problems. 

• • Wounds may not heal properly during treatment with Retevmo.
  • Tell your healthcare provider if you plan to have any surgery before or during treatment with Retevmo.
  • Thirdly You should stop taking Retevmo at least 7 days before planned surgery.
  • Your healthcare provider should tell you when you may start taking Retevmo again after surgery.

How should I store Retevmo?

• Store Retevmo 40mg capsules at room temperature between 68˚F to 77˚F (20˚C to 25˚C).
• Keep all medicines out of the reach of children and pets.

General information about the safe and effective use of Retevmo 40mg.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use this medicine for a condition for which it was not prescribe. Therefore, do not give it to other people. Retevmo selpercatinib 40mg tab price in india minimal at Yourmedikart. So even if they have the same symptoms you have. It may harm them. You can ask your pharmacist or healthcare provider for more information that is written for health professionals.

What are the ingredients in Retevmo?

Active ingredient: selpercatinib
Inactive ingredients: microcrystalline cellulose, colloidal silicon dioxide
Capsule: gelatin, titanium dioxide edible ink