Pemazyre 13 Mg (Pemigatinib) is a prescription drug that’s used to treat bile duct cancer and myeloid lymphoid neoplasms (MLN) with certain genetic markers. Also, Pemazyre 5 Mg cost comes as a tablet that you swallow. Pemazyre Pemigatinib 13 Mg / 5mg buy online at best price on Yourmedikart

Generic name: Pemigatinib [ PEM-i-GA-ti-nib]
Drug class: Multikinase inhibitors

Pemazyre (pemigatinib) is a targeted therapy known for treating certain cancers with minimal Pemazyre side effects. The Pemazyre price and pemigatinib price are competitive, reflecting its value in the pharmaceutical market. Available in Pemazyre 13.5mg dosage, it offers a precise treatment option for patients. Its counterpart, Penigatinib, is also recognized for its efficacy. Detailed information on Pemazyre 13 Mg price and Pemazyre Pemigatinib can be found by visiting the product page.

What is Pemazyre?

• Pemazyre is a kinase inhibitor that blocks the action of protein kinases.
• Pemazyre a prescription medicine used in adults to treat bile duct cancer (cholangiocarcinoma) that has spread to other parts of the body (metastatic) or cannot be removed with surgery. This medicine is usually given after your cancer has been treated with another medicine, and when the cancer has a certain type of abnormal FGFR2 gene. Your doctor will test you for this gene.
• Pemazyre was approved by the US Food and Drug Administration (FDA) for bile duct cancer on an “accelerated” basis. In clinical studies, some people responded to Pemazyre, but further studies are needed.
• Pemazyre is also used in adults to treat a type of blood cancer called myeloid/lymphoid neoplasms (MLNs) when the cancer has come back or did not respond to treatment, and when the cancer has a certain type of abnormal FGFR1 gene. Your doctor will test you for this gene.
• It is not known if this medicine is safe and effective in children.

Myeloid lymphoid neoplasms

With MLN, genetic mutations in the blood stem cells cause uncontrolled growth of certain blood cells. These mutated cells may accumulate in the bone marrow, blood, and other tissues, such as the spleen and lymph nodes. MLN may cause symptoms such as fatigue, weight loss, sweating, and fever.

If the genetic mutation is in the FGFR protein, your doctor may recommend Pemazyre. It’s typically prescribe when another medication hasn’t worked or when the cancer has returned following an earlier treatment.

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How should I take Pemazyre?

• Take Pemazyre exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
• For bile duct cancer, Pemazyre is give in a 21-day treatment cycle. Take Pemazyre 5 Mg cost one time each day for 14 days, followed by 7 days off treatment, to complete a 21-day treatment cycle. Your doctor will determine how long to treat you with this medicine.
• For myeloid/lymphoid neoplasms (MLNs), take Pemazyre  5 Mg cost one time each day.
• Take the medicine at the same time each day, with or without food.
• Swallow the tablet whole and do not crush, chew, break, or dissolve it.
• If you vomit shortly after taking Pemazyre 5 Mg cost, do not take another dose. Wait until your next scheduled dose time to take the medicine again.
• Pemazyre can cause you to have eye problems. An eye doctor will need to examine your eyes before you start taking this medicine, and every 2 to 3 months while you are taking it. Follow any instructions about using artificial tears or lubricating eye gel to treat or prevent dry eyes.
• Pemazyre can cause you to have high levels of phosphate in your blood. Your blood will need to test often. Your cancer treatments may be delay base on the results.
• You may be give other medication to help lower your phosphate. Keep using this medicine for as long as your doctor has prescribed.
• You may also need to follow a special diet. Follow all instructions of your doctor or dietitian. Learn about the foods to eat or avoid helping control your phosphate levels.

Dosing information

• Usual Adult Dose for Cholangiocarcinoma of biliary tract:
  • 13.5 mg orally once daily for 14 consecutive days followed by 7 days off therapy, in 21-day cycles until disease progression or unacceptable toxicity
  • Use: for the treatment of adults with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma with a fibroblast growth factor receptor 2 (FGFR2) fusion or other rearrangement.
• Usual Adult Dose for Lymphoma:
  • 13.5 mg orally once daily
  • Duration of therapy: Until disease progression or unacceptable toxicity occurs.

Comments:
-FGFR 1 rearrangement positivity status must know prior to the initiation of therapy.
-Assessment for FGFR 1 rearrangement positivity in tumor specimen should perform with an appropriate diagnostic test.

Use: For the treatment of adults with relapsed or refractory myeloid/lymphoid neoplasms (MLNs) with fibroblast growth factor receptor 1 (FGFR1) rearrangement

• Usual Adult Dose for Multiple Myeloma:
  • 13.5 mg orally once daily
  • Duration of therapy: Until disease progression or unacceptable toxicity occurs.
  • Comments:
    -FGFR 1 rearrangement positivity status must know prior to the initiation of therapy.
    -Assessment for FGFR 1 rearrangement positivity in tumor specimen should perform with an appropriate diagnostic test. Use: For the treatment of adults with relapsed or refractory myeloid/lymphoid neoplasms (MLNs) with fibroblast growth factor receptor 1 (FGFR1) rearrangement

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

To make sure Pemazyre 5 Mg cost is safe for you, tell your doctor if you have ever had:

• Problems with your eyes
• Vision problems; or
• Trouble swallowing pills.

You may need to have a negative pregnancy test before starting this treatment.

Both men women using Pemazyre should use effective birth control to prevent pregnancy. Pemazyre 5 Mg cost can harm an unborn baby or cause a miscarriage if the mother or father is using this medicine.

Keep using birth control for at least 1 week after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Pemazyre.

Do not breastfeed while using this medicine, and for at least 1 week after your last dose.

Pemazyre side effects

Get emergency medical help if you have signs of an allergic reaction to Pemazyre: Hives; difficult breathing; Swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• Eye problems–eye pain or redness, dry or puffy eyes, watery eyes, your eyes may be more sensitive to light.
• Vision changes–blurred vision, seeing black spots or “floaters,” or seeing flashes of light; or
• High phosphate levels in your blood–muscle cramps, numbness, tingly feeling around your mouth.

Your cancer treatments delay or permanently discontinued if you have certain side effects.

Common Pemazyre side effects in cholangiocarcinoma may include:

• Hair loss.
• Diarrhea
• Problems with your fingernails or toenails
• Feeling tired.
• Changes in your sense of taste
• Nausea, vomiting, loss of appetite
• Constipation
• Mouth sores, dry mouth.
• Dry eyes
• Joint pain, back pain.
• Stomach-area (abdominal) pain.
• High or low phosphate levels in your blood
• Dry skin.

Common Pemazyre side effects in myeloid/lymphoid neoplasms may include:

• Problems with your fingernails or toenails.
• Hair loss
• Mouth sores, dry mouth.
• Diarrhea
• Dry eyes
• Feeling tired
• Anemia
• Stomach-area (abdominal) pain.
• Rash
• Constipation
• Nose bleeds.
• Blurry vision, disorder of the retina
• Pain in feet or Hands
• Loss of Appetite
• Dry skin
• Indigestion
• Back pain
• Nausea
• Swelling in feet, legs, hands, or arms
• Dizziness.

What other drugs will affect Pemazyre?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may affect Pemazyre, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

What should be considered before taking Pemazyre?

Below is important information you should consider before taking Pemazyre 5 Mg cost.

Interactions

Taking a drug with certain medications, vaccines, foods, and other things can affect how the drug works. These effects are called interactions.

Pemazyre can interact with several other medications. Pemigatinib price It can also interact with certain supplements as well as certain foods.

Before taking Pemazyre, talk with your doctor and pharmacist. Tell them about all prescription, Pemazyre 13 Mg price over the counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

Drug Interactions

Below is a list of medications that can interact with Pemazyre. This list doesn’t contain all drugs that may interact with Pemazyre. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

FAQ

What is Pemazyre used for?

PEMAZYRE is a prescription medicine used to treat adults with bile duct cancer (cholangiocarcinoma) that has spread or cannot be removed by surgery: those who have received previous treatment, and. whose tumor had an abnormal FGFR2 gene.

What is the duration of treatment for pemazyre?

It is taken in a three-week cycle consisting of two weeks in which Pemazyre is taken every day, followed by one week without the drug. Treatment can continue as long as the patient is benefiting, and the results can be managed.

What class of drug is pemigatinib?

Pemigatinib belongs to a group of drugs called kinase inhibitors. It works by inhibiting the activity of abnormal proteins that signal cancer cells to multiply. This helps to stop or slow down the spread of cancer cells.

What is the generic name for Pemazyre?

Pemazyre (pemigatinib) is a kinase inhibitor used to treat adults with locally advanced or metastatic cholangiocarcinoma with a fibroblast growth factor 2 (FGFR2) fusion or rearrangement approved by the FDA.

Is Pemazyre a chemo drug?

PEMAZYRE is not chemotherapy; It is a targeted therapy for cholangiocarcinoma, meaning it can help prevent the spread of cancer by targeting specific molecular targets in cancer cells.

What is the difference between Lytgobi and pemazyre?

Pemazyre (pemigatinib) and Lytgobi (futibatinib) are kinase inhibitors used to treat certain types of cancer, but they target different genetic mutations and are approved for different indications.

Other interactions

Pemazyre 13 Mg can also interact with other substances, such as:

• Vitamins and supplements: Pemazyre interacts with St. John’s wort. Your doctor will likely recommend that you avoid taking this supplement during your Pemazyre 13 Mg treatment.
• Foods: Pemazyre interacts with grapefruit and grapefruit juice. Your doctor will likely recommend that you do not consume grapefruit products during your Pemazyre 13 Mg treatment.
• Alcohol: Alcohol is not known to interact with Pemazyre. However, alcohol may worsen certain side effects of Pemazyre Pemigatinib price, such as mouth ulcers and dehydration. Also, a study found drinking alcohol may make cancer treatments such as Pemazyre 13 Mg less effective.

Before starting Pemazyre 13 Mg treatment, Pemigatinib price talk with your doctor and pharmacist. Pemazyre 13 Mg price After that Tell them about all prescription, over the counter, and other drugs you take. Also, tell them about any vitamins, herbs, and supplements you take. Sharing this information can help you avoid potential interactions.

But if you have questions about drug interactions that may affect you, talk with your doctor or pharmacist.

Pregnancy and breastfeeding

You should not take Pemazyre Pemigatinib 13 Mg price during pregnancy or while breastfeeding.

At this time, there haven’t been any human studies of Pemazyre 13 Mg during pregnancy. But due to the way the drug works, Pemazyre Pemigatinib 13 Mg price it may cause problems with fetal development (commonly known as birth defects). It may also result in pregnancy loss. If you can become pregnant, your doctor will have you take a pregnancy test to confirm that you’re not pregnant before starting Pemazyre treatment.

Thirdly It’s not known whether Pemazyre Pemigatinib 13 Mg may be present in breast milk or what effects the drug may have on a child who is breastfed. But it’s not recommended to breastfeed while taking Pemazyre and for at least 1 week after stopping treatment.

Birth Control

It’s recommended that females* who can become pregnant use birth control during treatment with Pemazyre Pemigatinib 13 Mg and for at least 1 week after taking the last dose. Males* with partners who can become pregnant should also use Pemigatinib price contraception during treatment and for at least 1 week after the last dose.

Warnings

Pemazyre 13 Mg can sometimes cause harmful effects in people who have certain conditions. Because This is known as a drug-condition interaction. Other factors may also affect whether Pemazyre Pemigatinib price is a good treatment option for you.

So, talk with your doctor about your health history before you take. So Pemazyre 13 Mg price Also Be sure to tell them if any of the following factors apply to you:

• Liver problems
• Kidney problems
• Eye problems, such as a retinal disease or dry eyes
• Previous allergic reaction to Pemazyre
• Pregnancy
• Breastfeeding