Tecvayli Teclistamab 30 mg/3 ml get at best Price at Yourmedikart

Generic name: Teclistamab-cqyv
Dosage form: Subcutaneous injection. 30 mg/3 mL (10 mg/mL), 153 mg/1.7 mL (90 mg/mL).
Drug class: Miscellaneous Antineoplastics

 

What is Tecvayli?

Tecvayli (Teclistamab) is an FDA-approved medicine for multiple myeloma (a cancer of the bone marrow) that is used by adults who have not responded to at least 4 prior treatments. So Tecvayli  helps the immune system fight cancer cells by binding to them, allowing the immune system to recognize and attack the cancer cells.

Tecvayli is available under a special program called Risk Evaluation and Mitigation Strategy (REMS).

Tecvayli has emerged as a promising treatment in the realm of targeted cancer therapy. Despite the potential for Tecvayli side effects, its efficacy has caught the attention of many. The teclistamab price in India and the general Tecvayli price are critical for patients considering this treatment.

With teclistamab step up dosing, developed by Janssen as part of its innovative approach, it marks a significant advancement. Patients and healthcare providers interested in the latest treatments like teclistamab or its variants such as tecvaly and techvayli, can find valuable information and support through comprehensive online resources.

What is Tecvayli used for?

Tecvayli can be used in adults with multiple myeloma. This is a type of cancer that occurs in certain white blood cells called plasma cells.

You may be prescribed Tecvayli if past treatments didn’t work for your multiple myeloma, or if the cancer came back after past treatments. Specifically, Tecvayli is only approved for use in adults who’ve already tried at least four other medications that haven’t worked to treat their condition.

Tecvayli works by attaching to multiple myeloma cells and causing an immune response. This means your immune system attacks and destroys the multiple myeloma cells.

How will I receive Tecvayli?

• Follow all the directions on your instruction sheets.  Read the Patient Wallet Card about serious side effects and learn what symptoms to watch for. Keep the card with you at all times.
• Tecvayli is given by a healthcare provider as an injection under the skin (subcutaneous injection) in the stomach-area, thigh, or another area.
• Tecvayli is given in Step-up doses.
• This means the first dose is the lowest dose and is called Step-up dose 1. It is given on day 1.
• The second dose is a slightly higher dose and is called Step-up dose 2. It is usually given on day 4
• The next dose is the first treatment dose which is higher than step-up dose 1 one and step-up dose 2. The first treatment dose is usually on day 7 and  is usually weekly after that.
• You will need to stay in the hospital for 48 hours after Step-up dose 1, Step-up dose 2 and your first treatment dose. Talk with your doctor if you have any questions.
• You may be given other medications to help prevent serious side effects. Keep taking these medicines for as long as your doctor has prescribed.
• Your treatment with this medicine may be temporarily or completely discontinued if you have certain side effects.
• You will need medical tests before and during treatment with Tecvayli

Tecvayli Dosing information

Tecvayli is available as:

• 30 mg/3 mL (10 mg/mL) single-dose vial
• 153 mg/1.7 mL (90 mg/mL) single-dose vial.

Usual Adult Dose for Multiple Myeloma

Comments:

• Patients should hospitalize for 48 hours after administration of all doses within the step-up dosing schedule.
• Step-up dose 2 may be given between 2 to 4 days after step-up dose 1 and may be given up to 7 days after step-up dose 1 to allow for resolution of adverse reactions.
• First treatment dose may be given between 2 to 4 days after step-up dose 2 and may be given up to 7 days after step-up dose 2 to allow for resolution of adverse reactions.
•  Administer pretreatment medications 1 to 3 hours before each dose of the step-up dosing schedule, which includes step-up dose 1, step-up dose 2, and the first treatment dose to reduce the risk of CRS: corticosteroid (oral or intravenous dexamethasone 16 mg), histamine-1 (H1) receptor antagonist (oral or intravenous diphenhydramine 50 mg or equivalent), and antipyretics (oral or intravenous acetaminophen 650 mg to 1,000 mg or equivalent).

Before taking this medicine

To make sure Tecvayli is safe for you, tell your doctor if you have:

• An infection.

Pregnancy

• You may need to have a negative pregnancy test before starting this treatment.
• May harm an unborn baby. Use effective birth control while using Tecvayli Teclistamab price best at Yourmedikart and for at least 5 months after your last dose. Tell your doctor if you become pregnant.
• Do not breastfeed while using this medicine, and for at least 5 months after your last dose.

What are the ingredients of Tecvayli?

Active ingredient: Teclistamab-cqyv

Inactive ingredients: edetate disodium, glacial acetic acid, polysorbate 20, sodium acetate, sucrose, Water for Injection

Warnings

Tecvayli Teclistamab price best at Yourmedikart may cause side effects that are serious, life-threatening or lead to death, including:

• Cytokine Release Syndrome (CRS). Call your doctor if you have symptoms of a serious side effect, such as fever, chills, trouble breathing, vomiting, or severe tiredness.
• Neurologic problems. Call your doctor if you have symptoms of neurological problems such as headache, jerking muscle movements, numbness and tingling, tremor, double vision, problems walking, hearing loss.

Also Call your healthcare provider right away if you develop any of the signs or symptoms of CRS or neurologic problems listed below at any time during your treatment:

Due to the risk of CRS and neurologic symptoms, you will need to stay in hospital for 48 hours after all doses of Tecvayli that are part of the “step-up dosing schedule.” For more information about the “Step-up dosing schedule” see How will I receive Tecvayli? section below.

Tecvayli side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Tell your medical caregivers if you have signs of cytokine release syndrome (CRS), a serious side effect: fever, chills, trouble breathing, confusion, severe vomiting or diarrhea, fast or irregular heartbeats, feeling light-headed or very tired.

Tecvayli may cause serious side effects. Call your doctor at once if you have:

• Firstly Bruising, swelling, warmth, redness, oozing, or bleeding where an injection was give.
• Secondly Low white blood cell counts symptoms may include fever, mouth sores, skin sores, sore throat, cough.
• Neurological problems: symptoms may include headache, jerking muscle movements, rigid muscles, feeling restless, numbness and tingling, confusion, problems speaking, muscle spasms, tremors, double vision, changes in handwriting, problems walking, muscle weakness in body or face, hearing loss, burning, throbbing, or stabbing pain.
• Signs of infection: symptoms may include fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding; or
• Most Importantly Liver problems: symptoms may include loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common Tecvayli 30 mg/3 ml side effects may include:

• Headache.
• Nausea, Diarrhea.
• Tiredness, Weakness.
• Joint pain, Muscle pain in the back, chest, arms, and legs.
• Cold symptoms such as stuffy nose, sneezing, sore throat; or
• Fever, chills, cough with mucus, chest pain, feeling short of breath.

What does Tecvayli cost?

Whether you have health insurance or not, cost may be a factor when you’re considering Tecvayli Teclistamab price best at Yourmedikart. What you’ll pay for Tecvayli may depend on several things, such as your treatment plan.

Here are a few things to consider regarding cost:

• Cost information and savings coupons: After that You can visit Optum Perks* to get price estimates of what you’d pay for Tecvayli when using coupons from the site.
• Savings program: If you have questions about how to pay for your prescription, talk with your doctor or insurance provider. A program called Janssen Compass may also be available.

How does Tecvayli work?

Tecvayli Teclistamab price best at Yourmedikart attaches to immune cells called T-cells and to multiple myeloma cells, which causes an immune response. And This means your immune system attacks and destroys the multiple myeloma cells.

If you have other questions about how Tecvayli works, talk with your doctor.

Is Tecvayli safe for older adults?

Yes, Tecvayli Teclistamab price best at Yourmedikart is likely safe for older adults (ages 65 years and older). In studies, no differences in safety or effectiveness were report in adults ages 65–74 years compare with younger adults. However, there were not enough people ages 75 years and older in the studies to make comparisons for that age range.

In general, older adults may experience more severe side effects from taking any drug, including Tecvayli. Moreover, this may be because of other medical conditions that may affect how the drug works. For example, older adults have a higher risk of liver or kidney problems. This could raise the risk of side effects from a drug.

What should be consider before receiving Tecvayli?

Below is important information you should consider before starting Tecvayli treatment.

Interactions

Taking a drug with certain medications, vaccines, foods, and other things can affect how the drug works. These effects are call interactions.

Secondly It’s possible that Tecvayli may interact with other medications, herbs, supplements, foods, or alcohol. However, the manufacturer of Tecvayli did not check for interactions in studies of the drug.

Before starting Tecvayli 30 mg/3 ml treatment, talk with your doctor. Tell them about all prescription, over the counter, and other drugs you take. Also, tell them about any vitamins, herbs, and supplements you take. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, talk with your doctor.

Pregnancy and breastfeeding

It’s not know whether Tecvayli may be safe to receive during pregnancy. But based on the way that Tecvayli 30 mg/3 ml works, the drug may cause harm to a fetus.

After that It’s also not know whether Tecvayli Teclistamab price best at Yourmedikart is safe to receive while breastfeeding. But because of the possible risks, doctors will usually recommend that you do not breastfeed during your Tecvayli Teclistamab price treatment and for at least 5 months after your last dose.

Because if you’re pregnant or breastfeeding, or planning to become pregnant or to breastfeed, talk with your doctor before starting Tecvayli treatment.

Birth Control

Tecvayli 30 mg/3 ml may cause harm to a fetus. If you can become pregnant, your doctor will recommend that you take a pregnancy test before receiving this drug. In addition, you should use birth control, such as condoms, during your Tecvayli treatment and for at least 5 months after your last dose.

Boxed warnings

However, Tecvayli 30 mg has boxed warnings Source about the risk of neurologic toxicity and cytokine release syndrome. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). It alerts doctors and patients about drug effects that may be dangerous.

Because of these risks, Tecvayli Teclistamab price best at Yourmedikart is only available at facilities certified through a Risk Evaluation and Mitigation Strategy (REMS) program. The purpose of a REMS program is to help decrease the risk of serious side effects from a drug.

If you’re prescribe Tecvayli, your doctor will also give you a wallet card that you should carry with you at all times during your treatment. This tells other doctors or healthcare professionals that you’re receiving Also Tecvayli and what symptoms of neurologic toxicity or cytokine release syndrome to watch for.

See below for details on Tecvayli boxed warnings.

Risk of neurologic toxicity. Tecvayli may cause neurologic toxicity. Moreover, this condition can occur if the drug damages your nervous system. Symptoms of neurologic toxicity may include:

• Headache
• Difficulty moving or speaking.
• Restlessness
• Numbness or tingling
• Confusion

Lastly Neurologic toxicity was commonly report in studies. In some cases, so it can be severe or even life threatening.

Similarly Due to this risk, Tecvayli 30 mg/3 ml you’ll likely stay in the hospital for at least 48 hours after each of your first three doses of Tecvayli 30 mg/3 ml. In addition, you should not drive or operate machinery between the first three doses or for at least 48 hours after receiving your third dose. So, this is because the drug may cause neurological issues, such as with coordination or memory.

FAQ

What is TECVAYLI used for?

Tecvayli is a cancer medicine used to treat adults with multiple myeloma (a cancer of the bone marrow).

What are the side effects of TECVAYLI?

Nausea, diarrhea; fatigue, weakness; joint pain, physical pain in the back, chest, arms and legs; cold symptoms such as runny nose, runny nose, sore throat;

What kind of a drug is TECVAYLI?

Multiple myeloma is treated with Tecvayli and chemotherapy. However, each drug works differently to treat this condition. Tecvayli is a type of medicine called a monoclonal antibody. It works by binding to certain proteins in cancer cells of a certain type of white blood cell.

What is the difference between Talvey and TECVAYLI?

Isatuximab is a new immunotherapy used to treat multiple myeloma in adults where 3 other treatments have not worked. It is taken with pomalidomide and dexamethasone and belongs to the same drug as daratumumab. Isatuximab is usually given as a long-term infusion.

When was TECVAYLI approved?

Tecvayli was approved in October 2022 for the treatment of adult patients with RRMM who received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory drug, and an anti-CD38 monoclonal antibody.