Alecensa 150 Mg (Alektinib) manufacturerd by Roche | Alecensa 150 mg is used to treat a particular lung cancer | alectinib price in india

Alecensa 150 Mg

Roche

Generic Name : Alektinib

What is Alecensa Used For and Alecensa 150 mg price

Alecensa (alectinib) is a cancer medication that meddles with the development and spread of cancer cells in the body.

alectinib is used to treat a particular kind of non-small cell lung cancer that has spread to different parts of the body.

Alecensa is used just if your cancer has a particular genetic marker (an unusual “ALK” quality). Your doctor will test you for this quality. Alecensa 150 mg price in India is low. Alecensa price in India is low at yourmedikart.store Buy Alecensa Alectinib online at lowest price in India.

Description

ALECENSA (Alectinib) is a kinase inhibitor for oral administration. The molecular formula of Alectinib is C30H34N4O2 • HCl. The molecular weight is 482.62 g/mol (free base form) and 519.08 g/mol (hydrochloride). Alectinib is chemically described as 9-ethyl-6, 6-dimethyl-8- [4- (morpholin-4-yl) piperidin-1-yl] -11-oxo-6, 11-dihydro-5H -benzo [b] Carbazole-3-carbonitrile hydrochloride Alectinib HCl is a white to yellowish white block powder or powder with a pKa of 7.05 (alkali).

ALECENSA is available in hard capsule form, containing 150 mg of alectinib (equivalent to 161.33 mg of alectinib HCl) and the following inactive ingredients: lactose monohydrate, hydroxypropyl cellulose, sodium lauryl sulfate, hard Magnesium fatty acid and calcium carboxymethyl cellulose. The capsule shell contains hypromellose, carrageenan, potassium chloride, titanium dioxide, corn starch and carnauba wax. The printing ink contains Iron Oxide Red (E172), Iron Oxide Yellow (E172), FD&C Blue No. 2 Aluminum Lake (E132), carnauba wax, white shellac, and glycerol monooleate.

How should I take Alecensa?

Before you start therapy with Alecensa, your doctor will play out an exceptional test to ensure alectinib is the best therapy for your kind of lung cancer.

Follow all directions on your prescription label and read all medicine aides or instruction sheets. Your doctor may occasionally change your dose. Use the medication precisely as directed.

Alecensa works best if you take it with food.

Swallow the capsule and don’t crush, bite, dissolve, or open it.

If you vomit soon after taking Alecensa, don’t take another dose. Stand by until your next scheduled dose time to take the medication again.

You may require regular clinical tests to be sure this medication isn’t causing hurtful effects. Your cancer treatments might be postponed dependent on the results.

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Precautions You Must Know:

This medication Alecensa may cause vision changes or make you dizzy. Along these lines, you are proposed not to drive or use the machinery and do whatever needs readiness or clear vision. You need to restrict alcohol consumption.

Tell your doctor if you are hypersensitive to this specific medication or in the event you have some other allergies, as this item may contain inactive ingredients, which can cause allergic reactions. You can converse with your doctor for more details. tell your doctor or pharmacist about your medical history, for example, if you have any liver disease, slow heartbeat, kidney disease etc.

In addition, this prescription may also make you more sensitive to the sun. Along these lines, you need to restrict your time in the sun. Avoid tanning booths and sunlamps during treatment and use sunscreen and wear protective garments when outside.

Detail

It isn’t really said that this medication passes into breast milk or not. But there lies a possible risk to the infant so the breast-feeding is not recommended while using this medication and for 1 week after stopping this medication. It is better to consult your doctor before starting breast-feeding the child.

This prescription isn’t suggested during pregnancy as it might hurt an unborn child. It is important that you prevent pregnancy during this prescription interaction. In case you or your partner becomes pregnant then you must tell your doctor immediately.

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Side Effects

Most common side effects of Alecensa:

You can get medical help if you have signs of an allergic reactions like difficulty in breathing, swelling of your face, lips, tongue, or throat.

• Low red blood cells (anemia) – pale skin, unusual tiredness, feeling light-headed, cold hands and feet

• a light-headed feeling, like you might pass out
• kidney problems – a change in your urine color, little or no urination, swelling in your feet or ankles
• Felling very slow heart rate
• Muscle pain, tenderness, or weakness
• liver problems – stomach pain (upper right side), loss of appetite, easy bruising or bleeding, feeling tired, dark urine, jaundice (yellowing of the skin or eyes).

Before Taking This Medicine

If you are allergic to alectinib, you should not use alectinib. Tell your doctor if you have ever had: lung cancer, lung or breathing problems other than liver disease; or slow heartbeat. If the mother or father takes this medicine, alectinib may harm the fetus or cause birth defects. If you are a female, do not use alectinib if you are pregnant. Use effective contraception to prevent pregnancy while you are using this medicine and for at least 1 week after your last dose. If you are a male, if your sexual partner can become pregnant, use effective contraception. Continue to use birth control for at least 3 months after your last medication. If the mother or father becomes pregnant while using Alecensa,

Tell your doctor immediately. It is not known whether alectinib passes into breast milk or whether it will harm a nursing baby. You should not breastfeed during the use of Alectinib and for at least 1 week after the last dose.

Important Safety Information

Everyone reacts differently to treatment with ALECENSA. It’s important to know the most serious and most common side effects with ALECENSA.

Your doctor may lower the dose or stop treatment with ALECENSA if any side effects occur. Contact your doctor right away if you have any of the following side effects.

ALECENSA may cause serious side effects, including:

Liver problems (hepatotoxicity). ALECENSA may cause liver injury. Your doctor will do blood tests at least every 2 weeks for the first 3 months, and then 1 time each month and as needed during treatment with ALECENSA. Tell your doctor right away if you get any of the following signs and symptoms:

• Dark urine
• Pain on the right side of your stomach area
• Yellowing of your skin or the whites of your eyes
• Feeling tired
• Bleeding or bruising more easily than normal
• Feeling less hungry than usual
• Nausea or vomiting
• Itchy skin

Lung problems. ALECENSA may cause severe or life-threatening swelling (inflammation) of the lungs during treatment. Symptoms may be similar to those symptoms from lung cancer. Tell your doctor right away if you have any new or worsening symptoms, including:

• Trouble breathing
• Shortness of breath

• Cough
• Fever

Kidney problems.

ALECENSA may cause severe or life-threatening kidney problems. Tell your doctor right away if you have a change in the amount or color of your urine, or if you get new or worsening swelling in your legs or feet.

Slow heartbeat (bradycardia). ALECENSA may cause very slow heartbeats that can be severe. Your doctor will check your heart rate and blood pressure during treatment with ALECENSA. Tell your doctor right away if you feel dizzy, lightheaded, or if you faint during treatment with ALECENSA. Tell your doctor if you take any heart or blood pressure medicines.

Muscle pain, tenderness, and weakness (myalgia). Muscle problems are common

with ALECENSA and can be severe. Your doctor will do blood tests at least every 2 weeks for the first month and as needed during treatment with ALECENSA. Tell your doctor right away if you have any new or worsening signs and symptoms of muscle problems, including unexplained muscle pain or muscle pain that does not go away, tenderness, or weakness.

Breakdown of healthy red blood cells earlier than normal (hemolytic anemia). Hemolytic anemia can happen in some people who take ALECENSA. If this happens, you may not have enough healthy red blood cells. Your doctor may temporarily stop ALECENSA and do blood tests, if needed, to check for this problem. Tell your doctor right away if you experience yellow skin (jaundice), weakness or dizziness, or shortness of breath.

Before you take ALECENSA, tell your doctor about all of your medical conditions, including if you:

• Have liver problems
• if you Have lung or breathing problems
• Have a slow heartbeat
• Are pregnant or plan to become pregnant
• Are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take, including prescription medicines, over-the-counter medicines, vitamins, and herbal supplements.

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Warnings

Alecensa can cause serious or life-threatening side effects. If you have the following conditions, please call your doctor immediately: Heart problems-severe dizziness, very slow heartbeat; lung problems: fever, chest pain, cough, difficulty breathing; kidney problems-changes in the color of urine, low or no urination, Swelling of the calf; or liver problems: pain in the upper abdomen, dark urine, loss of appetite, yellowing of the skin or eyes.

FAQ

What is Alecensa used for?

Alectinib is used to treat a certain type of lung cancer. It works by slowing or stopping the growth of cancer cells. Alectinib belongs to a class of drugs known as tyrosine kinase inhibitors.

Is Alecensa a chemo drug?

This type of medicine is usually used to treat certain types of cancer. Alecensa belongs to a broader class of drugs called tyrosine kinase inhibitors.

Can Alectinib cure cancer?

The updated results of the ALEX clinical trial (NCT02075840) show that alectinib (Alecensa) is very effective in the treatment of ALK-positive non-small cell lung cancer (ALK-positive NSCLC cancer) and can significantly extend the median free survival. 34.8 months compared to 10.9 months for crizotinib

How long can you take Alecensa?

In the clinical trial of ALEX: NCT02075840, the time of taking Alecensa ranged from a few months to more than a year, with a median time of 18.6 months. Alecensa treatment is usually continued until the disease progresses or the patient has unacceptable side effects.

Does ALECENSA cause weight gain?

The following additional clinically significant adverse reactions were observed in patients treated with ALECENSA: weight gain (9.9%), photosensitivity (5.3%), stomatitis (3.3%), interstitial lung disease (1.3%), and drug-induced liver damage. (1.3%).